Protein FOG - a streptococcal inhibitor of neutrophil function
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منابع مشابه
Protein FOG--a streptococcal inhibitor of neutrophil function.
Several strains of group G streptococci (GGS) form aggregates when grown in vitro. Aggregating strains interact with fibrinogen, and this study reports the isolation of a novel self-associating and fibrinogen-binding protein of GGS, denoted protein FOG. Sequencing of the fog gene revealed structural similarity with M proteins of both GGS and group A streptococci (GAS). Analogous to GAS, GGS wer...
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Group G streptococcus (GGS) is a human pathogen of emerging clinical significance. It causes skin and soft tissue infections, occasionally resulting in life-threatening conditions such as sepsis and necrotizing fasciitis. We recently identified FOG, a novel surface protein of GGS with fibrinogen binding and immune evasion properties. Here we investigated the role of FOG in streptococcal primary...
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15 صفحه اولAssessment of neutrophil function--II. Laboratory tests of neutrophil function.
This is measured by a Boyden diffusion chamber. A filter separates cells, that can be labelled with radiochromium, and the attractant. Hence the number of neutrophils that move through the filter can be quantitated (Boyden, 1962; Ternowitz, 1985). One can also use a test in which there is migration of neutrophils under an agarose gel. Three wells are cut in agarose gel in a plastic tissue cultu...
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ژورنال
عنوان ژورنال: Microbiology
سال: 2004
ISSN: 1350-0872,1465-2080
DOI: 10.1099/mic.0.27269-0